Instructions for use of the veterinary drug Kovinan

Using the appropriate medications can make a big difference in our pets’ health. One such veterinary medication that is useful for treating a range of ailments in dogs and cats is kovinan. By using it correctly, you can make sure that your pet receives the most benefit from the treatment.

We will walk you through using Kovinan properly in this article. We’ll go over everything, from dosage to administration methods, to help you better handle the medical care of your pet. Understanding how to use Kovinan correctly is essential, whether you’re dealing with a specific health issue or just want to be ready for future needs.

You can contribute to making sure your pet receives the best care possible by adhering to these instructions. Let’s get into the specifics of using Kovinan to promote your pet’s wellbeing in a safe and efficient manner.

Description of the drug Kovinan

Covinan is a hormonal medication used to control female false pregnancy and sexual desire in cats and dogs. Dutch pharmaceutical company Intervet (Intervet International B.V.) developed the drug.

Almost all veterinary pharmacies carry the well-known medication Covinan.

The Intervet company was founded in 1949 in the city of Boxmeer (Netherlands). The purpose of the creation was the development and production of vaccinations for birds. The demand for manufactured goods was great, so the small company developed quickly. In 1969, it became known as Intervet International B.V. and became part of the largest pharmacological organization Akzo Nobel. Gradually, the Intervet brand became known throughout the world and the division entered the top three world leaders in the production of veterinary vaccines. Intervet again became a separate organization in 2006, and a year later it became a division of Schering-Plough, which is part of Merck & Co (Merck Animal Health or MSD). In Russia, this company is called OOO "Intervet" MSD Animal Health.

Release form of Covinan

One can purchase covinan as an injection suspension. It is filled into bottles made of dark glass. Every 20 ml bottle has a metal cap that is rolled up and a rubber stopper to seal it. Each medication unit is individually packaged in a cardboard box with an explanation. One bottle in a package can cost anywhere between 1700 and 1900 rubles.

Covinan is a cloudy white liquid with the potential to delaminate when stored. Shaking briskly will easily get rid of this.

The manufacturer’s MSD was previously listed on Covinan packaging; however, more recent versions list Intervet instead (both versions are available at veterinary pharmacies).

Composition of the drug

The following ingredients are present in the hormone medication:

• proligestone (active ingredient);
• food additives E-214 and E-218;
• polysorbate (surfactant);
• lecithin and sorbitan palmitate (emulsifiers);
• sodium citrate duhvodny (food additive E-331);
• potassium dihydrogen phosphate (a salt used to make an isotonic solution);
• macrogol 4000 (a substance that causes a laxative effect);
• water for injection.

How to properly store Covinan

According to the usage guidelines, Covinan needs to be kept in the following ways:

• in the manufacturer"s sealed packaging;
• separately from food and feed;
• out of reach of children;
• in a dry place protected from direct sunlight;
• at a temperature of 2°C to 25°C;
• within 3 years from the date of manufacture.

It’s important to use the suspension right away after opening the bottle. Medicine that is not needed should be thrown away right away. Additionally, medication that has spoiled or expired (like a darkened suspension) shouldn’t be used.

The best place to keep Covinan and other veterinary medications is in a first aid kit.

Indications for the use of the suspension

For cats, covinan is used in the following situations:

• regulation of sexual hunting;
• Prevention and treatment of false pregnancy;
• Prevention and treatment of pseudolactation.

When a cat has a false pregnancy, she experiences all the symptoms of pregnancy even though she is not actually pregnant. The animal experiences physiological changes and has a hormonal background and neuropsychic state. The cat feels pregnant during this time, and it might start to exhibit signs of pseudolation and t. D.

How Covinan acts

The proligstone, which is the only active ingredient in Covinan, is the hormonal. This artificial steroid component influences the pituitary gland’s hormone secretion. The ovaries’ inability to produce follicles and the uterine cavity’s increased viscosity are caused by the absence of these hormones. As a result, the mammary glands’ secretion is disturbed and fertilized eggs are unable to attach. This explains why the medication has a contraceptive effect. However, the blood’s hormone levels return to normal when the medication is stopped.

Proligestone builds up in the body, so its effects don’t go away right away when the medication is stopped. When the material enters the intestines with bile, the majority of it is eliminated with feces. Urine excretes the remaining portion of the proligestone.

Features of use in cats

It is recommended to apply Covinan subcutaneously. It should not be permitted to administer drugs intradermally or allow them to enter scar tissue or the subcutaneous fat layer. Before injecting, it is advised to treat the injection site with alcohol or a solution containing alcohol. Before using, the suspension needs to be thoroughly shaken. Accurate dosage calculations and treatment regimen design are essential for successful use and attaining the intended result.

Video: how to properly give a subcutaneous injection to a cat

Table: selection of the drug dosage

Animal body weight	Single dose of Covinan
Up to 2.5 kg	From 0.5 to 0.75 ml
Up to 5 kg	From 1 to 1.5 ml
From 5 to 7.5 kg	From 1.5 to 2.25 ml
From 7.5 to 10 kg	From 2.25 to 2.5 ml

Scheme of application of Kovinan

One injection during the resting period is required if you wish to prevent sexual hunting once (within 3–4 months after the last estrus). However, if we are discussing continuous use, then you must adhere to the following schedule:

• first injection during the resting period;
• second injection 3 months after the first injection;
• third injection 4 months after the second injection;
• then the drug is administered every 5 months.

Once my mother was going on a long trip, and she had no one to leave her cat (Dusya) with. It so happened that at that moment I had a stranger"s cat in my care, and we did not plan to mate Dusya. When she was brought, I noticed signs of pre-heat (there was discharge, but she did not let the cat near her). I had no choice but to take the animal to the vet. Dusya was given a shot of Kovinan, and the cat did not bother her anymore. True, the first couple of days I had to look after the animals, but for the remaining 2 weeks the cat calmly coexisted with the male cat.

Precautions

There are a few guidelines that need to be kept in mind when using the medication:

• before and after contact, hands should be washed with warm water and soap;
• if the drug accidentally comes into contact with the skin or mucous membranes of the eye, they must be washed;
• people with hypersensitivity to the components should avoid direct contact with Kovinan;
• in case of allergy or accidental ingestion of the drug, you must immediately contact a medical facility;
• empty bottles of the drug are prohibited from being used for household purposes, they must be disposed of with household waste.

Rubber gloves and other personal protective equipment can help you avoid coming into direct contact with the medication.

Possible side effects and contraindications

The following animals cannot be treated with kovinan:

• pregnant and lactating cats;
• cats in heat;
• cats with pathologies of the genitourinary system;
• cats that have had discharge for a long time.

Diabetes is not a contraindication for using Covinan, despite some veterinary professionals’ opinions to the contrary. In these situations, the medication may be administered under a veterinarian’s supervision because ongoing blood sugar monitoring is required.

The cat may occasionally have adverse effects, such as:

• pain at the injection site (immediately after the administration of the suspension);
• the fur may become lighter at the injection site (less often, hair loss occurs in this area of ​​the body);
• the cat may gain excess weight (hormonal imbalance);
• gluttony or, conversely, indifference to everything;
• enlargement of the mammary glands;
• uterine inflammation (pyometritis, endometritis, etc.). d.).

Covinan has a 0.6% chance of side effects, which is not very high.

I questioned the vet about why the instructions mention potential side effects when they might not materialize. I was informed by the veterinarian that this is done for safety. For instance, it doesn’t necessarily mean that the medication wasn’t effective if a cat’s mammary glands suddenly swell. Without treatment, this phenomenon may pass (though it’s still advisable to take the cat to the veterinarian). However, if this effect is not mentioned in the instructions, the owners may make poor choices and hurt the cat—for example, by giving the medication to the cat more than once.

See a veterinarian before administering hormonal medication to a cat as it may have unfavorable effects.

Combination of Covinan with other drugs

With the following exceptions, covinan can be used with other veterinary medications:

• estrogens (Estrone, Estradiol, etc. d.);
• progestins (Proligestone, Mepregenol, etc. d.).

When Kovinan is used in conjunction with other hormonal agents, the likelihood of side effects increasing increases.

Analogues of the drug according to indications for use

The closest Covinan equivalents are:

• Kovinavet (Russia);
• Kastril (Ukraine);
• Depo-Provera (Belgium).

Table: comparison of analogues of Covinan

Name	Active substance	Release form	Contraindications	Side effects	Price
Kovinavet	Proligestone	Suspension for subcutaneous injections	Cannot be used in the following cases:

• pregnant and lactating cats;
• during estrus, in the late stages of pre-estrus;
• in diseases of the genitourinary system;
• animals with prolonged vaginal discharge of uncertain etiology.

• pathologies in the tissues of the uterus and ovaries;
• increase in animal weight;
• increase in appetite, apathy;
• enlargement of the mammary glands;
• lightening or loss of hair at the injection site.

• in diseases of the genitourinary system;
  in the presence of a tumor of the mammary glands;
• together with other estrogens and progestogens;
• during puberty;
• during estrus, pregnancy or lactation;
• in case of intolerance to the components of the drug.

Photo gallery: Kovinavet, Kastril and Depo-Provera

Although Depo-Provera was created with women in mind, it is now being used more and more to prevent cat ovulation. Although not found in every Russian pharmacy, Kastril is a less expensive substitute for Kovinan. Similar to Kovinan, Kovinavet can be found at any veterinary pharmacy, and the average cost of these medications is comparable.

Step	Instructions
1	Read the label and instructions carefully before use.
2	Measure the correct dosage based on your pet"s weight.
3	Administer the medication as directed, usually by mouth or injection.
4	Monitor your pet for any adverse reactions.
5	Consult your vet if you have any concerns or if symptoms persist.

Your pets’ health will greatly improve if you use Kovinan as prescribed, ensuring that their condition is effectively treated. Achieving the best results while reducing potential side effects is made easier by adhering to the provided guidelines.

Make sure you are always aware of the dosage and administration guidelines that are unique to your pet’s requirements. Depending on your pet’s weight and health, adjustments may be necessary, so it’s important to speak with your veterinarian before making any changes.

After giving Kovinan to your pet, keep a close eye on them and be aware of any negative reactions. To address any concerns or unusual things you notice, get in touch with your veterinarian right away.

To keep the medication effective, it must be stored properly. Make sure it’s out of children’s and pets’ reach and store it somewhere cool and dry, away from the sun.

You can promote your pet’s successful recovery and guarantee their wellbeing during Kovinan treatment by following these guidelines.

Knowing how to use veterinary medication like Kovinan correctly is essential to maintaining the health of your pet. Kovinan is intended to treat a variety of conditions in pets. Simple directions for using Kovinan are provided in this article, along with crucial safety advice and dosage recommendations. This guide will help you use Kovinan to support your pet’s well-being, whether you’re new to using it or just need a refresher.

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